SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41e762e0f8c74993472ab400376a0e7849339ef7c0d9cd79f0d187228c9f01ca' 
  AND token = 'cBvl1Lghbx2zBFsMY8R3Qk5W6VBJA9Vc2sYThiolm5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}