SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81e708a299667d2e3f0710264cd5efcb68c6053c0c9189414a717e09f998d21e' 
  AND token = 'MF+zCEg9t2z531xijvngiINnyZHEGldwMCZl3Y50Ty0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}