SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84c5861bcb2b9dc6fd27b1c084e5c0a7f0e806b66385dd54350580f56c84161d' 
  AND token = 'IBzJgPPqK2IZa2DPcQ7KxxjwGL88766cZ3PQ82se/rQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}