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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e0526e3b4d5ca2c0be3588268e87b78bb81f0d78077a463af1aba159a48f6d' 
  AND token = 'vdHEn8TsLS5wSk6AJxqdqA40C7s+8flvDmbeCP1Zhgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}