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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e24b81897505130d5acf5e05d756c641c4751af33534bcc465ac7ba3d07f513' 
  AND token = 'EP7UL29D0hN+ERXkFleK0trHF1ceuYV2rAaTte8gyLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}