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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2287c4c8edd207044be14ef26162f5072efeb93628e7d68c0629ad10acdfbb0' 
  AND token = 'LKa4p14pdIf/B+xI6d9nDWlFjBtPm8dCbQiLPV0CYsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}