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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d036d380ecad7a2b6f957b81b657457c3a7378ceadadfe4fa6cf049a763df03' 
  AND token = 'qE1XCNA2GNlVgWl3y2lycr+VewAUoUF90zu/czFfaOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}