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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43415cfb5b771fab224da5c0194c43bdcc1e6cc4b16ee75924c3c6674c642d90' 
  AND token = 'CRm69ZCwNBhTQw9wLpcB5HxIauAV3xMdnwlyiMzbO78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}