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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da9663c21f3fb626b1c83e28de70034aaad762a91d189b23ba8dbd9c4f80e237' 
  AND token = 'PZhipDj37c5x7Uy7x/2IPtupGZr0zWHqwFPHW3j2vZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}