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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e2f99dd340c31ad57ceb456fae8327e5d5e1455d61f7cb4b4156af1b09792d9' 
  AND token = '5DcFkbAGTpYiY21ehDkBz8HT7Di7pqh0LVrl1V+LZU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}