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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04b4ddd0f85d06318e95c1b50e681fbba40df913b049bfc386a43fcc6f39df99' 
  AND token = 'f2wMcaDLthG1bg3OOvFjHEhBAvECwJmDWSCGpni7b1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}