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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdcf140078897a671a9a794cf1eb7b2b731180285b314dbee3f4a137dab9f9a3' 
  AND token = 'LREGviix8RdqRNksrgaCo43jpG595stED0Z0G8rbOEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}