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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b69c1fd6292fa49f70b1187405a2d015008d89951a71bf9c65a5bb79af10507' 
  AND token = 'I80TjzAz2D61jCaRLebiPjKh8OdASMqH5oZN/Lpm2TU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}