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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4210ac34fb220e78e0f47449fa10a96cb77490b94b7805ebb1d22eddf1d086cf' 
  AND token = 'FUcA44nZ1eKRalu/MgAG2dG793d+wIjmFO7X1LmEjJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00079

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}