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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '470f7205aac7c0ff8345209b2b6c61eb5a24255f8c2644e9f388105a2b51c207' 
  AND token = 'teQesI6wnt3k56lfb2+apQ4Nq4FQ98JBLqTcoD6b4Y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}