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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cefc6071a5f685e7cacdda19a2596269182733fabb41629730c2c40c1eba4b44' 
  AND token = 'HbvUB4Mo8X2xTQqTcHBQRDXFjzrlupvb/PPsH21A16c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}