SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ccde284aa82bb2a1c04db6904dba214e7c9f20182a1527ea0736b944f23961e' 
  AND token = 'V0UY8BbCH0NvNto0XoZbfQF1hCbykLbxFoIjnbrHN8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}