SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6156150af228b99d484c2c87ea2c3cead620f45fab99a1aea42ffdf964f7f453' 
  AND token = 'gtC51yjtC3yRjhcjHwy1/hw3+p/y6qhzDpWpVPEU6nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}