SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '864ffcc87f1d5aa7ba34cfd4120d81e0a67a4e23bc1d297220b4794481351eac' 
  AND token = 'la60roGrEaMf55aw9/ufWsfDhW74PsDIvW/J6GmVqbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}