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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29eefbc37f53af2f4480a133c5af32d9e1139040263b77285e83d1807b8bc217' 
  AND token = 'dlhTSWQyZR9R1R6S7FJzIt5r3KoAIHoXnspu1ha//x4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}