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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ade6a7e959dee42551e3282fa4be1e30db14f50b27482970bdddf6cd7994705' 
  AND token = '/kfj6E4szz5qR3vU8iauNr0mCIItvatyuKv8ObbSnDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}