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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c677ca54eb054e8469161db2a9700cbe1515e7d72a9939a06ae8fb1848e18b9' 
  AND token = 'iP6eJUefXdyU61A0H090d0nu029K8xi2dZqlqxXH2zA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}