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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c66828b2a10a8696cd16617ce67802996427e7260f8d84b109d3d9ea6516a1db' 
  AND token = 'gBwKqhW+CmZhhGW3NoX8QPmWLuXnEd4z5OGcUK9iIto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}