SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '343420711a26bc9c0bc8087e7d5ee685e109d9c4084fb5982f25c84b467240a1' 
  AND token = '77XwdBf1rGX4CSM9KJFVdCaXRWhIJseWp13hpHi7Ahw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}