SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61f525377bba9b7afc0a7ed7404fc1b2e766ec75be708d8ed1202d7bbbf1f27f' 
  AND token = 'bDXjUsKR1N74H8nmEBDRvsuesNrD8uIhkRwH7fMvJmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}