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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de61130c01431d1573045409e606984f90dde86e4df3de98e848e40a3e745966' 
  AND token = 'yl4UJ7xlOeCu9SXJf1GY7uL/y1JaMWK9eW7TiM6z0S8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}