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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ee66e1b98dcf683fd805e232bc06f6ff55bac39a142957dc11eea709a80c764' 
  AND token = 'HzM76TYxoj7EEcP1oKIBq9QdYyi+2Rmscg9HwGy5l9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}