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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85fe1f08b10533a4f3a790a125e9911a33cc2a332f902c257c10c2d56360b8e9' 
  AND token = 't1HQDl403i21f/Ybo1RpGhq+GGTTX1yTVUua+UdEUTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}