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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd80facd9144c3620f10cb85706f9d2d786da27182f4d30617e695748da10d4bd' 
  AND token = 'nH0osZ5Bt6DFpvQo4SI69Cnoc6AxpxUNBnUA8DYa8II=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}