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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00f2c16897fa5fb6e713204eff13d08436380b43ae15d389d7123d6b2b0f8727' 
  AND token = 'qLCGo8oue3MppZHr5K/9UXk6mbFaBbh2W7q9sgYbDXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}