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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8391e3695921699151d6dcb77e415e07e37c52b3aaac5dc6ac16f592022bc07' 
  AND token = 'PwklFT9t/c9N8dnoHJg7ewGwRNvlFxskqmzOxuLAWy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}