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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3f9a9320ed59391b1b82a15bb5aaaf0b3463c01a8a1939bbc0a24d98175c0c6' 
  AND token = 'E5Znt2MzKk88ays0rKwkpwI+9dcXbOVRFbLCPU22Zyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}