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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10a01a38e548b4ebbcd6bec6c3b68c6f0fb9ac0d71f9e555f840dd4b3bf61d05' 
  AND token = '35JBXizrSf4kc/pJxgXFjohHkiLuQoeNB8XOWaAe6E4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}