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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54350597a02ed33b5d127daae231abe5565a42ba33c2cb060ceaff1ab59810e0' 
  AND token = 'lV0fCzjyeJAa0yaLoQ4we+S+zeFONXT3KcSMjPuQiZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}