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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1514c016345cca0d27f4f83aec64c3d655b6d1820e9301b633d9b508405d9f9' 
  AND token = '75Y+TTm0BffydN8m68k0bmyNJG7hkm0+RAW5h2AUf7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}