SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a707dfcc5a054bef09e6700a1670654ab816940650b99a4cae88000445b88fa' 
  AND token = 'fvCxzs+QqTuXCsOQtQzs5KOUQaUL2hZrlKQ5Vjh0VU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}