SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18ef0de4dcdaee972d09b214da2f22ac2469b18b70238dac1a3e861c29ab1e98' 
  AND token = '6F68rdsW08LNaISgLj7VsWMwIwgHuixQNEsGbzB0b28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}