SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d9d45933ef65871dd987c4f0af4b0fb59844e417c485b4fbda8afa9a4619b89' 
  AND token = '8Ous8/dKf0OE6RD6kCvVLjYk2T6jUMxWPMg4iPkOmgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}