SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d66a15f17939a75692382084c106d6bf3a292fca62cee70c7f441553cbf8eb4' 
  AND token = 'jAUueNLU0q0gyYkog6IHVTnOgyaRpxodKSNaduMF3hY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}