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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df7a624f41a9fd7ea4110a140fcd9801929d4b1d8904e2020f28ef80ca36b1b8' 
  AND token = 'vgMaeeZpgeIUixM5cDX5sNWIRFDYpE2B2nwTqyY1LW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}