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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df59115c97f260e235ecfd7f8e37cba208dff75f84c71859d7eda8ea4b46a557' 
  AND token = 'G3r2izKQWM6AWTHTc09Q8VzJg+bwNiXxDHJFtsZc8/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}