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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e747b0c125322b5cfafd72eaf0e36bca27c00375b1274eb7d3caac5569b6935' 
  AND token = 'FYy0Xyfo3rWk0DmM2BTK5XF7VJs60yI/a4AqkTyGAx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}