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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3e3a0ce3b4c75e3ed3351de1c70e0fe08112518a96a5778e3e9a4d7bbba5053' 
  AND token = 'E+H6lq9Bztu7/UFiD1uTtFjnLhnjhIvNLvp/t8VJE2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}