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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d05ac1df1fcd9e4553f7b24c2c57afb24f3461bf9aadfc7109038c09ee1387f' 
  AND token = 'A0T+88YX4PyTJeGrmkjYWlY4q2Tc1GYUM4bQJHZkOwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}