SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c2edde5b90765e86c0d0e1671ee731d759baf183f0b22a48d29b0feb1e3d89c' 
  AND token = 'MBz7I/IwxRGxlYEGT3V1YJUmp77FqIDcRV5jMtoD4X4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00079

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}