SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b0013ea636850ab7cf8b8db38a6b8d7fd0382e581a61291113272f4596a8ddf' 
  AND token = 'N1xg3HCSmj0OmJOfRCddwrzVtQaWo1JqeBKsw78jDWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}