SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fe2e1c42d7dd98ade732bd80c9cfc14423cf3fd496c3b5b11db8dbb883052aa' 
  AND token = 'U0fUchC5OgggR7+4L1PMio/XsgHH6FLezOpnLn1mxNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}