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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de0f90c048515507e14af82c0c6f12505533aa5a38b5fa649cca83dc2c793f29' 
  AND token = '+PMxHZx+/UHeLCN8wRtJRr/ukyOup82/eGUHFgSosIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}