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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc6a43c53080f9491bfedfba5677aaad602bf29a093d0aa4074fb28fa2c7e15f' 
  AND token = 'lUx1oFT663KEtqFHPPqa+pkh7tBI11sJVxiU8rLf5bU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}