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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d70a8f486ac993e71bec252651d158a79566cccd42fe3e11f086b8e939ea1e1' 
  AND token = 'lW5M6uieZZMW8bRG7a95mM3lI/gpWIAeCW7wZHwJKoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}